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In-111 Pentreotide (OctreoScan)

This radiotracer, which binds preferentially to somatostatin receptor, is used to localize PNET tumors.

Go back to Oncology (Nuclear) imaging. 


Normal biodistribution

Picture
4 hours after tracer injection: Blood pool, normal thyroid, kidneys and bladder, liver, gallbladder, spleen

24 hours after tracer injection: Blood pool, normal thyroid, kidneys and bladder, liver, gallbladder, spleen, and bowel (as seen in the image above) 


Image
Courtesy of SLEH

Patient Preparation

Octreotide acetate therapy should be discontinued 1 day if standard preparation, or 4 weeks if long acting/slow-release, before In-111 pentetreotide is administered.

Protocol

SNM Procedure Guideline for Somatostatin Receptor Scintigraphy 2.0 (ver 2.0, 2011)

Notes

Pheochromocytoma has classically hyperintense signal on T2W MR images.
- RM at Endocrinology MDTB in 7/2014
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